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Welcome to the University of Pittsburgh Institutional Review Board (IRB) online submission process, also known as OSIRIS (Online Submission for Institutional Reviews)

Good Clinical Practice (GCP) Training

All Investigators and research team members who are engaged in the conduct, oversight or management of clinical trials (as defined by the NIH) must complete the CITI GCP training course before they participate in any research activities effective January 1, 2017. The University is extending this requirement to all research studies that meet the definition of a clinical trial regardless of the funding source. It is the responsibility of the Principal Investigator to ensure that all members of the research team who meet this requirement complete GCP training and maintain certification during the course of the study.


For general information about the University of Pittsburgh IRB and OSIRIS, go to www.hrpo.pitt.edu.

Login to OSIRIS:

  • You will need a username and password from HSConnect.  If you need to create an account, go to www.hsconnect.pitt.edu.  It is important that you do not create duplicate accounts.  If unsure, contact us at irb@pitt.edu or HSConnect support team at 412-648-2222.

  • You must have completed the required CITI training available at www.citi.pitt.edu.

Your HSConnect username and password is used to log into both the CITI and OSIRIS sites.

If you need more information about obtaining your username and/or password, navigating OSIRIS, or other IRB related questions, please review the General Information page, available from the link on the left side of this page, or contact us at irb@pitt.edu.

Thank you for using OSIRIS!



Sandbox Blurb

Click here for information on accessing the OSIRIS Sandbox